Identification of SNP Markers in Pm4b gene of Wheat – Part2

Molecular SNP markers are regions of DNA with variations. They help in selecting desired traits for plant breeding. Pm4b is a gene of interest that imparts the desired resistance against powdery mildew, a fungal disease in certain breeds of wheat. Samples with and without the Pm4b gene were taken for the identification of SNP markers … Continue reading “Identification of SNP Markers in Pm4b gene of Wheat – Part2”

Identification of SNP Markers in Pm4b gene of Wheat – Part1

Food – Primary source of essential nutrients to the whole world. When enquired on for one’s favorite food, we get to hear a wide variety of preferences from worldly cuisines. Most of these dish recipes would have wheat as a common ingredient. Wheat is a grass variety cultivated for its edible grains and is widely … Continue reading “Identification of SNP Markers in Pm4b gene of Wheat – Part1”

Text Mining & NLP analysis of SARS-CoV-2

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): A 50-200 nm virion with a genome size of approximately 30000 nucleotides paused the normal and routine activities of the world by being the causative agent of Coronavirus Disease 2019 (COVID-19). Several questions came flooding when I started to know more about this novel coronavirus. The researcher in … Continue reading “Text Mining & NLP analysis of SARS-CoV-2”

Strand NGS-Annotation toolbox for organisms

Our planet accommodates a variety of life with their genes: from civilized humans to the colonized bacteria, from infamous mosquito to the cutest puppies, and from golden rice to the greenest algae. Studying these species helps us in understanding the genetics of the species and population diversity and also other biomedical and bio technical applications. … Continue reading “Strand NGS-Annotation toolbox for organisms”

What’s new in Strand NGS 3.4

Data quality is of utmost importance for accurate and valid downstream NGS analysis. Sequence artifacts contribute to erroneous interpretations in analysis. Focusing on this, we have introduced two quality checks to find Overrepresented Sequences and Adapter Content. Trim these sequence artifacts in further steps for accurate downstream analysis Strand NGS 3.4 now supports Agilent UMI … Continue reading “What’s new in Strand NGS 3.4”

Webinar on Diagnosis of Rare Diseases using NGS Based Multi-gene Testing- Case studies 18 Apr

A disease is considered to be ‘rare’ when it affects one in about 2000 individuals in the population. This, individually are although rare, collectively, the incidence could be very high causing a significant socio-economic burden. Arriving at a confirmatory diagnosis is a major challenge in these inherited disorders, which can significantly impact treatment and disease … Continue reading “Webinar on Diagnosis of Rare Diseases using NGS Based Multi-gene Testing- Case studies 18 Apr”

Live Webinar: Integration of NGS and Machine Learning for prediction of post-operative recovery

Webinar on Integration of NGS and Machine Learning for prediction of post-operative recovery on 9 Aug, 8 am PST About Speaker:  Mario Deng MD FACC FESC , Professor of Medicine, Advanced Heart Failure/Mechanical Support/Heart Transplant, David Geffen School of Medicine at UCLA, Ronald Reagan UCLA Medical Center Abstract: Strand NGS supports a comprehensive and flexible RNA-Seq data analysis workflow consisting of Alignment, … Continue reading “Live Webinar: Integration of NGS and Machine Learning for prediction of post-operative recovery”

Strand NGS-Calling narrow and broad peaks from ChIP-Seq data

Know about the state-of-the-art algorithms implemented in Strand NGS for detecting the binding sites of transcription factor (narrow peaks) and enriched regions of histone modification (broad peaks) from ChIP-Seq data. Read the benchmarking study on Calling narrow and broad peaks from ChIP-Seq data in Strand NGS by Rohit Gupta and Anita Sathyanarayanan. For more information, … Continue reading “Strand NGS-Calling narrow and broad peaks from ChIP-Seq data”

Interesting findings by ChIP-Seq and DNA-Seq analysis using Strand NGS

The year 2014 was a great year with exciting features and enhancements updated in Strand NGS. We take this opportunity to thank our clientele and well-wishers for their support and feedback. We wish you all a happy and prosperous new year and look forward to a more fruitful engagement in 2015. In this blog on … Continue reading “Interesting findings by ChIP-Seq and DNA-Seq analysis using Strand NGS”

From yeast to mice to chicks to stem cells – 4 ways RNA-Seq analysis sheds light on the world around us (a four part series)- Part II

In my previous blog post, I had walked you through a yeast paper where the authors had mapped its mitochondrial trancriptome. They had used the RNA-Seq analysis tool from Avadis NGS in clever ways to figure out details about the transcriptome that played a key role in piecing together the final map. In this week’s … Continue reading “From yeast to mice to chicks to stem cells – 4 ways RNA-Seq analysis sheds light on the world around us (a four part series)- Part II”