Webinar on Unique Molecular Identifier (UMI)-powered Ultra-sensitive Variant Calling using Strand NGS on 13 Dec at 2:30 PM and 9:30 PM IST by Dr.Pandurang Kolekar

Unique Molecular Identifiers (UMIs) are short random nucleotide sequences that are increasingly being used in high-throughput sequencing experiments. In this webinar, we will highlight the UMI-friendly features of Strand NGS v3.1 including support for handling well known and customised UMI libraries, QC metrics, consensus alignment, UMI-based family size filters for read list, genome browser enabled … Continue reading “Webinar on Unique Molecular Identifier (UMI)-powered Ultra-sensitive Variant Calling using Strand NGS on 13 Dec at 2:30 PM and 9:30 PM IST by Dr.Pandurang Kolekar”

Decoding Breast Cancer using Strand NGS DNA Variant analysis

One of the most dreaded diseases mankind has faced in recent times is cancer. Because of high morbidity and mortality rates that cancer brings it is a fearsome disease. When we hear about cancer no one believes that it can happen to them or to anyone else close. But the reality is far from this. … Continue reading “Decoding Breast Cancer using Strand NGS DNA Variant analysis”

Strand Life Sciences to showcase Strand NGS, analysis software for next-generation sequencing data at ASHG 2017

Scientists from Strand Life Sciences will demonstrate ‘Strand NGS’, an all-in-one next generation sequencing software at the 67th Annual Meeting of the American Society of Human Genetics (ASHG) to be held from Oct 17 to 21 in Orlando, Florida.Strand is excited to be an exhibitor at ASHG 2017 and will use this opportunity to showcase … Continue reading “Strand Life Sciences to showcase Strand NGS, analysis software for next-generation sequencing data at ASHG 2017”

The tyranny of large numbers: mutations in breast cancer

What’s in a number? Small numbers are roguish capsules of triple meaning. The number 7 is the date you were married; it’s the exact number of teaspoons of sugar in a halwa recipe your mom sent you; it’s the age of your eldest son on his next birthday. As we get older, we become acquainted … Continue reading “The tyranny of large numbers: mutations in breast cancer”

Accuracy puts the there in speed: DNA-Seq stuff!

In certain circles, asking why speed is good is tantamount to heresy. I once submitted a paper with the phrase “computational performance is not an explicit goal of this work” in the abstract. It was rejected; in his explanatory note, the reviewer had said that my approach was “unlikely to yield great speedups,” and that … Continue reading “Accuracy puts the there in speed: DNA-Seq stuff!”

Seeing is Believing – Genome Browser and Elastic Genome Browser in Strand NGS

The unending desire and quest to unravel and see what lies beneath the deepest layers have always pushed humans to improve upon anything and everything that they touch. This curiosity in a way has led to never thought before technological advances.  One of the most important discoveries of all the times has been the discovery … Continue reading “Seeing is Believing – Genome Browser and Elastic Genome Browser in Strand NGS”

It’s pronounced three dot oh

Getting things to “just work” is hard. Getting them to just work and be good is harder. With StrandNGS 3.0, we believe we’ve done both. A quarter year’s labour of love, three dot oh feels different because it is different; it feels good because it is. RNA alignment is faster. If you’re using transcriptome + genome alignment, you … Continue reading “It’s pronounced three dot oh”

Rare diseases: or, what happens when backups fail

Ploidy is a funny old Greek word for a modern, almost modish concept: data backups. Ploidy is the number of copies of an organism’s DNA. Certain kinds of algae, for instance, don’t buy into backups; they’re haploid, and contain only a single copy of DNA. Plants, on the other hand, are polyploidal; paranoiacs of the … Continue reading “Rare diseases: or, what happens when backups fail”

Celebrating 25th Release announcement of Strand NGS

We are happy to share the announcement of the 25th release of Strand NGS (v2.8). We started our journey as bioinformatics experts in 2000, and moved into the next-generation sequencing space with the launch of Strand NGS (formerly Avadis NGS) in October 2010. Since then we have grown with our customers, added more workflows, features, … Continue reading “Celebrating 25th Release announcement of Strand NGS”

Reduce the SNP annotation time by up to 95%

Explore the new script ‘Create Targeted VAL’ in Strand NGS for creating subset of dbSNP database with target regions of interest and run your analysis. This feature reduces your SNP annotation time by up to 95% depending on the target regions of interest. Strand NGS v2.7 has more exciting features. Listed below are few: