The silent biomarkers of stem cells- Small RNA

I was watching this movie, where the protagonists were a race of human clones made from “stem cells” and they try to defend their lives from the native human race. You might have already heard of dolly the sheep, the first cloned animal out of an adult stem cell. Also, the infamous CRISPR babies whose … Continue reading “The silent biomarkers of stem cells- Small RNA”

What’s new in Strand NGS 3.4

Data quality is of utmost importance for accurate and valid downstream NGS analysis. Sequence artifacts contribute to erroneous interpretations in analysis. Focusing on this, we have introduced two quality checks to find Overrepresented Sequences and Adapter Content. Trim these sequence artifacts in further steps for accurate downstream analysis Strand NGS 3.4 now supports Agilent UMI … Continue reading “What’s new in Strand NGS 3.4”

Ultra-sensitive variant calling and transcript quantification using Unique Molecular Identifiers

Background Next Generation Sequencing (NGS) technologies have remarkably revolutionized the medical and genomics research. The incremental cost reductions and size of the throughput at molecular resolution helped penetration and acceptance of the NGS methodologies into worldwide labs and clinics. The third generation wave of NGS technologies are knocking the doors to provide impetus to the … Continue reading “Ultra-sensitive variant calling and transcript quantification using Unique Molecular Identifiers”

Webinar on Unravelling complex mutational events in clinical cases using the power of NGS data analysis on 31 Jan

Live webinar on Unravelling complex mutational events in clinical cases using the power of Next generation sequencing data analysis by Dr Satish Sankaran on 31 Jan 2018 at 9am CET and 8am PST Speaker: Dr. Satish Sankaran, Vice President- Clinical Operations and Laboratory Director- Clinical Lab, Strand Life Sciences Pvt Ltd Abstract: Next Generation sequencing has come a … Continue reading “Webinar on Unravelling complex mutational events in clinical cases using the power of NGS data analysis on 31 Jan”

The clinical workflow, retinoblastoma and split alignment

    Retinoblastoma is an “oma” named for its surface effect, its “presentation”:  it’s a cancer that attacks the eye. Worse, because 80% of retinoblastoma diagnoses occur before the age of 3, it’s a cancer that attacks the eyes—almost exclusively—of little children. Retinoblastoma is a “good cancer”: 90% of all RB cases survive into adulthood. … Continue reading “The clinical workflow, retinoblastoma and split alignment”

Webinar on RNA-Seq Data Analysis

Strand NGS supports an extensive workflow for the analysis and visualization of RNA-Seq data. The workflow includes Transcriptome / Genome alignment, Differential expression analysis with Statistical approach and Splicing events detection. Strand NGS also supports novel discovery like identification of novel genes, exons and Novel splice junctions, alongside it can also detect gene fusion events. … Continue reading “Webinar on RNA-Seq Data Analysis”

Webinar on Implications of Next Generation Sequencing in Molecular Diagnosis of Cancer

Genetic testing requires screening of the entire gene, which by conventional sequencing is time consuming and expensive. Next Generation Sequencing (NGS) based approaches increase the sensitivity of mutation detection, making it fast and cost-effective compared to the conventional tests performed in a reflex-testing mode. Strand NGS includes workflows with quality assessment and filter sections that … Continue reading “Webinar on Implications of Next Generation Sequencing in Molecular Diagnosis of Cancer”

Celebrating 25th Release announcement of Strand NGS

We are happy to share the announcement of the 25th release of Strand NGS (v2.8). We started our journey as bioinformatics experts in 2000, and moved into the next-generation sequencing space with the launch of Strand NGS (formerly Avadis NGS) in October 2010. Since then we have grown with our customers, added more workflows, features, … Continue reading “Celebrating 25th Release announcement of Strand NGS”

Reduce the SNP annotation time by up to 95%

Explore the new script ‘Create Targeted VAL’ in Strand NGS for creating subset of dbSNP database with target regions of interest and run your analysis. This feature reduces your SNP annotation time by up to 95% depending on the target regions of interest. Strand NGS v2.7 has more exciting features. Listed below are few:

Strand NGS v2.7 released

We are excited to share the release of Strand NGS v2.7. This new version comes with several exciting features and enhancements. Listed below are few major enhancements: